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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

中国富人近年来对岛屿表现出越来越浓厚的兴趣。
[m?s]

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

12岁女孩发现古埃及护符
The second most sought-after job, according to Zhonggong, was a position offered by the regional earthquake bureau in the Inner Mongolia autonomous region, which had 768 applicants as of Tuesday.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

She's the perfect choice for this role, having hosted the Oscars last year, and previously hosted the Grammy Awards and the Primetime Emmys.

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 购买期房 你必须知道的知识
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

When it was set up in 2002, Teach First’s aim was to encourage more graduates to try teach-ing. Amid worries that the best brains in the country were being lured into the City of London, accountancy and law, the idea was to tap some of their brain power for state schools, in an attempt to tackle educational inequality.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

今年世界卫生组织宣布H1N1型流感为全球性传染病。庆幸的是,这种病毒远没有人们最初想的那样危险,而最新面世的疫苗似乎已经平息了那弥留在人们心头久久不能散去的恐惧。
2. LinkedIn. Brand love: 47% / Rank: 309
['i?ju:]
?备用发电机的失败使得纽约大学医院分部的Langone医学中心被迫撤离。大约200名病人被迫转移。官员们正在调查备用电源失败的原因。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Will impeachment proceedings begin against Donald Trump
寨卡病毒的后果
现在,我们来说说2010年。
选择出国继续学习的学生比例也出现小幅下降,由去年的4.8%下降至3.4%。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

在1月10日发表的一条推文中,奥巴马写道:“感谢你们为我做的一切。我最后一个请求和第一个一样。我请求你们不要相信我的而要相信你们自己的创造改变的能力。”

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

That calm can sometimes be taken for a lack of the urgency that is vital in the fast-moving tech industry. Many were disappointed that Apple Watch was not made available to buy this year. But analysts say Apple’s approach of waiting until it has perfected a product usually leads to stronger long-term performance. Samsung, whose smartphone sales have suffered this year, is on its sixth-generation smartwatch, but has still not found a real hit.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

早在2008年,从测量心率到根据用户情绪播放音乐等的一系列可穿戴技术就已经被吹捧为消费电子产品的下一个重要契机了。
节目1 开场曲《欢歌贺新春》,中央电视台48位主持人

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

注册人数:511人
那些原本希望今年凭借战术策略获得些利益的财务顾问和资产配置人员,也在反复无常的市场中栽了跟头。全美前三位的战术策略产品中,有两款产品几乎因为高达两位数的亏损而崩盘,还有一款产品则因为向公众误报自身历史回报率而受到美国证交会调查。另一家战术产品巨头嘉信理财旗下90亿美元的Windhaven Diversified Growth产品,2014年的回报率几乎为零。战术策略原来不过如此。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Wright is one of the most original figures of British Romantic painting, and this composition, held in the same private collection in Derbyshire since 1840, had an approachable low estimate of 100,000 because of condition issues and — not insignificantly — the fact that it was a charity donation to benefit Syrian refugees. As a result, at least three bidders pushed the price to 665,000 with fees.
反对:在某种程度上,《三块广告牌》分裂了美国观众,它赢得最佳影片的希望或许会因此破灭。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

In addition to WeChat's core private and group messaging functions, users can also find new contacts by using the application's Drift Bottle function, where a user records a message and sends it out to see in a virtual bottle for a stranger to pick up and respond. Its Look Around function, similar to some mobile dating applications, allows users to browse the profiles of other users who are in close proximity. It also has a function called Moments that allows users to share photo albums publicly with groups of contacts, much like photo-sharing application Instagram.
这是007系列电影最佳主题曲之一,但实际上并没有在片头演奏,所以我们把它放在荣誉推荐的第一位。这首浪漫的曲子呼应了电影情节的发展,最终詹姆斯·邦德遇到了真爱。(可惜他们的恋情维持不久便结束了。)路易斯·阿姆斯特朗运用了他标志性的颤音,听者心弦颤动,一个经典诞生了。
BETTER CALL SAUL (AMC, Feb. 8) Vince Gilligan and Peter Gould’s “Breaking Bad” spinoff is probably the most anticipated new series of the winter. Starring Bob Odenkirk as the crooked lawyer Saul Goodman, the show is set before the action of “Breaking Bad,” so any appearances by Bryan Cranston or Aaron Paul would be cameos at best. But the audience favorite Jonathan Banks reprises his role as the phlegmatic enforcer Mike Ehrmantraut.
The president lashed out at the UN on Sunday for voicing human rights concerns over his war on drugs, saying the Philippines might leave the organisation and form a new body with China and African nations.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Apple CEO Tim Cook

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 北京房企深耕产品IP价值
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

"He was not on the intelligence services' radar," added the prime minister.
circulate圆,环+ion→发生,流通

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

“…called the interviewer by the wrong name.”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

After Google and Apple, are Amazon and Microsoft.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

But Mr Stevenson said “this might reflect that the US is being bolder than the EU in protecting domestic steel producers”.
Against: Strong in many categories, but without quite managing to be a front runner in any. Perhaps Timothee Chalamet's performance is its best chance of awards success.
Gitanjali表示,她想要进一步改善改设备,这样它最终就能进入市场了。
岁数最小的富豪是来自挪威的企业继承人亚历山大·安德森,她今年只有19岁。亚历山大20岁的姐姐是岁数第二小的上榜富豪。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 3525套保障房为北京留住更多人才
Review Article

Influenza neuraminidase: A druggable target for natural products

4. HHhH
这之后,场均进球数一直在下滑。2010年南非世界杯上,这一数目跌至2.27个,仅次于1990年意大利世界杯的2.2个。
圣加伦大学在校友满意度方面排名居首。
而诺贝尔物理学奖则颁给了三位生于英国、目前正在美国工作的科学家,肯定了他们对极端状态下物质的特异属性所做的原子级研究。
n. 轨道(track的复数);磁道;轮胎

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

他告诉《中国日报》:“中国医生每天要看多少病人?可能超过50个。我们怎么可能有时间和精力做研究或发论文呢?”
其中一本被标上"M3"的坟墓里包含有神兽的雕刻,其中有四只代表一年四季以及天堂的各个部分:西边的白虎,南边的朱红鸟,北边的黑龟,东边的青龙。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 中国智能家居或因无专利集体阵亡
Critical Review

The role of biosensors in the detection of emerging infectious diseases

马自达获得了最佳轿车品牌的称号。汽车媒体一直很青睐马自达的表现,而如今的马自达汽车都在精致的内部设置和强大的驱动力上赢得了积极的反馈。上图的2016马自达第三代,在美国新闻小巧车排名中摘得桂冠,它的精准操控,强大加速度和高端室内布局,赢得了大多数汽车评论家称赞。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

2016年空前的海外收购潮消耗了中国大量外汇储备,随后监管部门开始严格限制境外交易。今年8月,中国政府出台了新框架,鼓励那些符合北京战略重点的交易,并限制涉及娱乐、体育和豪宅等方面的交易。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

每季度,英特尔(Intel)都会铺上红地毯,欢迎加入公司的新员工。在入职培训的第一天,每位新人都会受到摄影师和摄像师的夹道欢迎,上台做完自我介绍,新人们就能领取一份欢迎大礼包(还有周围新同事们的热烈掌声)。
“我们希望这份榜单会让大家采取措施保护自身的网络安全。”
虽然出现上述下跌,但保费收入同比增长37.3%,至1.88万亿元人民币,保险业资产总量达到14.27万亿元人民币,增长了15.42%。
进入前五强的还有桑德拉·布洛克(Sandra Bullock),是我们榜单中仅有的两位女演员之一(另一位是排名第十的詹妮弗·劳伦斯)。布洛克出演了两部电影题材迥异的热门影片:《地心引力》(Gravity)是一部紧张刺激的惊险片,有望使她再次获得奥斯卡提名;而《辣手警花》(The Heat)则是一部票房成绩不俗的喜剧片,全球票房收入达2.3亿美元。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

A study published in the journal "Clinical Psychological Science" in 2012 showcased the power of self-imagination, which showed the technique could help people with impaired memories, as well as individuals with no memory problems. As with other studies of human memory, the scientists asked participants to remember a list of words related to certain personality traits. The participants were then asked to use a specific strategy to help them recall the words. For example, some participants were asked to remember one personality trait by thinking of a second word that rhymed with the trait. Other participants were asked to remember the definition of the trait while others were asked to engage in "self-referential processing" where they would think about the trait in a personal, self-reflective way.
Frankly, this is unlikely to be ready in time for next year, but we'll include it just in case. The second film from Laszlo Nemes, who won the foreign language Oscar earlier this year for Son of Saul, is a coming-of-age drama set in Budapest just before the first world war.
数据显示,三星仍然占据榜首,其次是苹果。但是即便如此,这前两名的科技公司的出货量却分别下降了3%和7%,全球市场份额出现了下滑。
英国新人结婚模仿“怪物史瑞克”(图)

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

announced
The U.S. Congress and the media will go berserk when Goldman announces the size of its 2009 bonus pool. But the outrage will be brief and of little lasting consequence. The 'hate Goldman Sachs' story has been running just too long.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

历史会这样回首2012年:这一年,中国“第五代”领导层亮相,同时中国经济转向较低速增长的轨道。这种转变发生的背景,将是一系列令人畏惧的国内挑战——不断增加的社会不安定,不断扩大的收入差距,以及生态和人为的灾难——加上不断升级的外部紧张,这源于美国重新转向亚洲,同时亚太邻国对中国的经济崛起越来越感到忧虑。
route
Stanford's Zhenan Baohas has developed a super-flexible, super-durable, and super-sensitive material that can be the basis for future synthetic skin. People have tried developing synthetic skin before, but Baohas's material handles touch sensitivity better than any predecessor. It contains organic transistors and a layer of elastic, letting it stretch without taking damage. And it's self-powered—this skin contains a series of elastic solar cells.
美国选举人团制度已经在两方面失效。
阿方索?卡隆(Alfonso Cuaron)凭藉广受好评的全球热门太空科幻影片《地心引力》(Gravity)赢得最佳导演奖。《地心引力》、《美国骗局》和《为奴十二年》均有可能成为今年奥斯卡奖(Academy Awards)的夺奖热门,本周四将公布今年奥斯卡奖提名名单。(与金球奖不同,奥斯卡奖还设置技术类奖项。)

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

The first drone can be traced back to 1916 when British inventor Archibald Low designed and flew the first unmanned radio-controlled vehicle. The drone was made to counterattack German Zeppelin airships, and it also carried out ground attacks during World War I. It was made with wood and tin, its wings taken from the lower wing of another biplane. Overall, the drone was somewhat unsuccessful because the noise from its engine interfered with its radio. The Sopwith Aircraft Company also tried making a drone in 1916. They placed the radio equipment at the tail so that the engine would not interfere with its signal, but their drone never flew as it was damaged in an accident on the ground. Low would try flying his drone again in 1917 when he flew it in front of some senior military officers. It was launched from the back of a lorry and flew for some time before crashing due to engine failure, almost killing the military officers present.
连续4年以来,排行榜前5名的位置都被相同的五个跨洲EMBA项目所占据。Tiemba项目今年能够荣登榜首,不是因为它比竞争对手表现得异常优秀,而是得益于在大多数指标上的强劲表现。尤其是,该项目学员的平均薪资(32.4万美元)排名第二,仅次于凯洛格-香港科大(Kellogg-HKUST)EMBA项目的学员(40.8万美元)。Tiemba项目在职业晋升方面也位居第二,在工作经验方面排名第四。
你可能从未想过一根皮带可以与人工智能相结合,但Belty做到了,并使它看起来很时尚。这个belty会让你不自觉就觉得,“为什么我需要这个?”然后你想可能会是,“如果是黑客入侵,他们把它系得很紧我不能呼吸该怎么办?”第一个问题是合理的;第二个问题有些牵强,但如果它让你三思而后买这个产品,这并不是一件坏事。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

挪威两度拒绝成为欧盟成员国,整体排名为地第十。“公民权益”排名第一,“最透明”国度排名第二。
该银行在其报告中称:中国是否减持库存将成为2017年棉花和糖市场的主要价格推动因素,玉米、大豆或植物油可能也是如此。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Judge Business School at the University of Cambridge jumps five places to fifth. Not only is it the first time it has broken into the top five, but it is also the first occasion that LBS is not the top-placed UK school in the MBA ranking.
研究人员写到,对于1700年前的中国朝代来说,如果能征服并有效的管理龟兹的话,那么他们就能够控制住西域所有的绿洲城邦。
乔布斯在苹果博览会上展示iPod mini ,2004年1月6日,旧金山

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

我的预感是到了3月份,今年的应考新秀们就会看起来很棒,并且会远比去年要好,去年是近几年来最不被看好的一年。新奥尔良和华盛顿都需要一个明确的方向,并且他们不久就会做出各自的选择。
7. Pemuteran, Indonesia-Bali's pemeturan has sites for scuba diving among coral-covered Buddha statues, while ground-level offerings include beachfront resorts and restaurants.
近两年P2P贷款行业迅速发展。根据E-Lending House,截至6月底,该行业未清偿贷款达2090亿元人民币。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 恒指高开0.14% 多只内房股冲高
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

In the past two decades, several campus poisoning incidents have sparked mass debates and concerns about students' psychological development and support.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

But retail sales growth softened to 10 per cent in October, betraying economists’ expectations it would hold steady at 10.7 per cent growth from September.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

单词lasting 联想记忆:
"Now more attention is being paid to the second generation of stars and rich people, but in fact the second generation of migrant workers needs more attention."

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Over the past three years, drawing conclusions about China's box office growth has been complicated by Beijing's decision to include new service fees in official revenue totals.
In 1995 Dutch troops serving as UN peacekeepers failed to prevent Bosnian Serb forces murdering 8,000 Muslim men and boys in the town of Srebrenica in eastern Bosnia.
在上月销量最高的SUV和MPV制造商中,大家所熟悉的长城汽车和上汽通用五菱汽车成功卫冕。在轿车和掀背车型上,上汽大众也保持其冠军地位。
联系方式:Staci Donegan and Peter Westley, Celia Dunn Sotheby’s International Realty, (912) 247-2052 / (912) 660-5169; celiadunnsir.com

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

'But then what I do is I nudge him with a little reference to a newspaper article he happens to glance at which just reminds him that these things will give him cancer.
n. 经营方法,行为态度

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

3. Your boss received your résumé from a contact of a contact。
In the Robot World Cup Soccer final on June 30th the Dutch robots weren’t up against the Chinese team “Water” from Beijing. Within a minute the Chinese team scored a goal. The Dutch made an equalizer before half-time, yet in the second half team Water scored again.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

源于:strike(v 打击;军事进攻;铸造;敲钟;罢工)

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

China does not want to see a trade war between the US and China. That would not make our trade fairer and cause loss for the both sides.
而或许更引人关注的问题是,雅虎究竟为何决定拿出3,000万美元来收购一款手机应用呢?诚然,Summly的文本精炼能力与新战略下的雅虎对移动设备的侧重不谋而合。伴随着以11亿美元对轻博客的收购,以及广受好评的新款天气应用的推出,Summly软件的加入见证了雅虎占领智能手机领域的坚定决心,以及为爱使手机的年轻消费者提供优质服务的不懈努力。
大多数人对瑞典的印象是“一个阴冷而美丽的国度”。但这并非概括瑞典的全部。作为斯堪的纳维亚半岛上面积最大的国家,瑞典人口却十分稀少,对于那些厌倦嘈杂、喜爱静谧生活的人来说,瑞典可以说是人间天堂。在这样舒适的环境中,品尝新鲜海鲜、浆果以及特色奶酪等当地美食,是再合适不过了。
The unemployment rate probably won't fall quite as rapidly in 2015, according to economists, especially if more people enter the labor force because jobs are easier to find. Yet another large spate of hiring similar to the gain in 2014 would make the low unemployment rate more believable.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.
贾斯汀比伯名列第五,因他为慈善组织Pencils of Promise和Believe Charity Drive做的贡献。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

[iks'p?nn]
vt. 记载,(用文件
Mila Kunis placed second on the list, followed by Kate Upton, pop star Rihanna and Emma Stone.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

坚持依法全面履职。
在《星球大战:原力觉醒》后,迪士尼影业和卢卡斯影业承诺每年冬天推出一部星球大战系列电影,都将围绕原来的主题展开。
Goldie Blox是一家玩具公司,使命是重新定义玩具商店中的“粉红走道”。在科学、技术、工程和数学(STEM)教育和职业领域,男性数量要大大多于女性,大部分女孩往往在八岁前就对这些领域失去了兴趣。Goldie Blox所设计的玩具则通过吸引女孩发展强大的口头及故事讲述能力的方式——同时仍提供机会来发展日后可转化成对工程学兴趣的技能——来鼓励和启发未来的工程师们。说到机会,一家玩具初创企业如何能在和一开始就统治着玩具行业的大公司的抗衡中脱颖而出呢?Goldie Blox走出了明智的一步:最近,该公司发布了一段视频,采用了Beastie Boys的歌曲《女孩们》(Girls)做背景音乐,该视频得到了病毒式传播。尽管这段视频最终被撤下,但Goldie Blox在提高公众对让更多女性和女孩对STEM产生兴趣——以及对Goldie Blox玩具——的认知上,做了一份相当不错的工作。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

We will boost the development of modern agriculture.
Chinese mainland is home to two of the top three universities in Asia, according to research published last Thursday by the Times Higher Education (THE).

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Its return to the throne came at a cost to London which, after occupying pole position for two years, is trading places with its Asian rival.
7)让我来唱黑脸:想找一种婉转的批评方式?将对话转变为一场操练,你在其中扮演被孤立的一方,执行一项职能:戳穿(对方言语中的)逻辑漏洞及其攻击计划中的漏洞。你使用此条策略,一定要强调一点,千万不要在这些观点中掺杂个人情绪。
['?mnesti]

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

She only learnt to walk five months ago, but 'Baby Beyoncé' is already strutting her stuff on stage at pageants.
China’s handling of its state reserves of raw materials such as cotton and sugar will be a key factor shaping the direction of agricultural commodities in 2017, according to a major lender to agribusinesses.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Call Me by Your Name
Will China’s reported gross domestic product growth surpass 6.5 per cent
凯莎《彩虹》

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

怎么做煎饼?

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

阿里巴巴旗下品牌淘宝位居第二,品牌价值429亿美元,超过了中国移动、百度和中国工商银行。
Good luck, good health, hood cheer. I wish you a happy New Year.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

根据康奈尔大学、英士国际商学院和世界知识产权组织联合发布的这一份报告,这使得中国成为中等收入经济体中该指标的领先者,紧随其后的是已经超过巴西的印度。
That comes in spite of official figures released on Tuesday showing China’s exports had contracted for a second straight month in October, suggesting domestic demand is the main driver of price gains for producers.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

奥巴马取得胜利,也以为着在接下来四年的发展道路:关于国家开支、税收、医疗健康、政府的角色,还有应对中国发展和伊朗核问题等的外交措施。
这也是这座大都市连续第8年保持全国最大消费城市地位。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 解析LED行业“钱景”大趋势
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

《楚乔传》改编自网络小说《11处特工皇妃》,讲述了女奴楚乔的奇遇以及她和燕洵世子的爱情故事。
直播平台的观众可以给主播送需要花钱买的虚拟礼物。礼物的价格从0.1元到1000元不等。直播平台从中抽取一定比例的提成。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

John Stevenage, chief executive of British Mensa, said he was delighted for Nishi. He said: 'I hope she will make full use of her membership to meet new, like-minded people and challenge herself. Joining Mensa opens the door to an international network of more than 100,000 people and many members make friends for life.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

在家里创造一个属于自己的学习空间。如果身边家人都在身边,你就要确保大家都明白你是在里面学习,除非房子着火,他们是不会打扰到你的。
英国会是七国集团(G7)中经济增长最慢的国家吗?
今年年初,所有华尔街经济学家都呼吁提高利率,彭博社就这个问题调查了67位经济学家的意见,他们全票赞同,有鉴于此,任何一个有理性的人都不会想要增持对利率敏感的公用事业股。把赌注押在金融股上的投资者,回报进展缓慢;而瞅准了“低价”能源股的投资者,投资组合业绩在第一和第二季度曾因此推高,却在第三和第四季度被大拖后腿,可谓“成也萧何,败也萧何”。
8月11日

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

He took out his textbooks and busied himself with his daily homework routine.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 中装新网建材频道隆重上线
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

10. “移动珠宝”(Run the Jewels),《移动珠宝2》,Mass Appeal。说到迫切和讥讽,杀手麦克(Killer Mike)和EL-P都是地下说唱界不同圈子里的资深人士了,他们组成的“移动珠宝”在第二张专辑里找到了坚实的互相吸引。他们的说唱强大有力,关注点狂热喧闹,专辑抨击没有让任何人摆脱困境的权力结构。
Or maybe you've become bolder in arguing against decisions you disagree with, Foss says. "Any variation to what's expected of you or from you could raise an eyebrow," she adds。
安娜的头发比查斯顿本来的发色浅,有时安娜向后撩头发时会露出这两个层次,有点戏谑,但仍不失威严。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

"I am a doctor and I prefer to speak frankly. A person's health is related first to eating, drinking and air. Any kind of development will be nothing if the quality of food, water and air is not good." ZHONG NANSHAN, NPC deputy and academic with the Chinese Academy of Engineering
LBS’s programmes consistently rank highly for the extent to which alumni reach their targets. “I managed to achieve not only the goals I set for myself but to exceed them with the job I secured,” says one 2010 MBA graduate who responded to the FT survey.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Rossello also has pledged to work closely with a federal control board that U.S. Congress created last year to oversee Puerto Rico’s finances, and he has said he supports negotiations with creditors to help restructure a nearly $70 billion public debt.
《自己土地上的陌生人: 美国右翼的愤怒与哀悼》(Strangers in Their Own Land: Anger and Mourning on the American Right)一书的作者阿莉?罗素?霍克希尔德(Arlie Russell Hochschild)对路易斯安那州的农村社区进行了四年的研究,她认为那里“深藏着”一种失去机会的感觉。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 增城、黄埔大盘二手房火力全开
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Writing for a Variety Special: Patton Oswalt, “Patton Oswalt: Talking for Clapping”

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

However, five Beijing-based travel agents said they were still selling South Korea tours for March, as was China’s largest online travel company Ctrip. Representatives at the top three state-owned airline carriers in China told Bloomberg they had not received instructions to halt ticket sales to the country.
该研究还表明,通过实习找工作或许有价值。接受录用通知的实习生的薪酬水平超过那些收到录用通知但拒绝的实习生。那些没有收到录用通知的实习生的薪酬水平更低。这些群体间的薪酬差距在毕业3年后扩大。
裘德韦伯(Jude Webber)

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

She is now so successful that her mother has hired a security team who monitor the star 24/7.
Stanford’s alumni have the highest salary on average at $195,000 but overall the top 15 MBA programmes are closely matched in terms of income, career progress and satisfaction. All but one have average alumni salaries greater than $150,000, with a pay increase of about 100 per cent compared with their pre-MBA income.
勒布朗·詹姆斯
4. Con Dao Isalsnd, Vietnam-Once the site of the infamous Con Dao prison, Vietnam's isolated archipelago of 16 islands known as the Con Dao Islands is starting to become known for its scenery and fresh seafood.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

《巴克斯托姆》(Backstrom),Fox,1月22日播出。去年,福克斯推出根据一部澳大利亚电视剧《法庭浪子》(Rake),由格雷格·金尼尔(Greg Kinnear)主演,讲述一个自毁律师的故事。那部剧没成功,但现在Fox又试着推出了一部根据瑞典系列小说改编的自毁侦探的故事,由《办公室》(The Office)男星雷恩·威尔森(Rainn Wilson)主演。这部剧由Fox的系列剧《识骨寻踪》(Bones)的编剧哈特·汉森(Hart Hanson)主创,但在试播集里,威尔森饰演的巴克斯托姆看上去更像豪斯医生(House),而不像《识骨寻踪》里的角色。
改革就是要解放和发展生产力,调动广大人民的积极性,让群众得到实惠,为政之要就是要舍小利、顾大义、顺民心。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

新美国基金会(New America Foundation)高级研究员李?德鲁特曼(Lee Drutman)在一份给Vox的分析文章中指出,在阿肯色州、北卡罗莱纳州和田纳西州,移民人口是1990年的三倍以上。围绕这些变化产生的焦虑或许可以解释共和党为什么在这个阶段更关注限制移民问题,还有这些州的白人投票者们何以压倒性地支持特朗普。
Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.
Kristen Stewart definitely did some 'butt' kicking at the Nickelodeon Kids' Choice Awards 2013 on Saturday. The star strutted down the purple carpet in a dazzlingly deep blue and black top and tiny shorts that had a miniscule checkerboard pattern. Kristen was nominated for two awards at the live show - Favorite Movie Actress for The Twilight Saga: Breaking Dawn - Part 2 and Favorite Female Buttkicker for Snow White and the Huntsman.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Other notable custom course performances include Harvard Business School, which recorded one of the year’s biggest rises, jumping nine places to fifth. The Massachusetts school was ranked 18th two years ago.
"The Hunger Games" star ranks first on the 2012 edition of AskMen.com's "Top 99 Most Desirable Women" list. The poll, which collected more than 2.4 million votes, asked the website's readers to choose their favorite female celebrities based on their looks, personality, talent and other desirable characteristics.

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