Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
The second most sought-after job, according to Zhonggong, was a position offered by the regional earthquake bureau in the Inner Mongolia autonomous region, which had 768 applicants as of Tuesday.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
She's the perfect choice for this role, having hosted the Oscars last year, and previously hosted the Grammy Awards and the Primetime Emmys.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
When it was set up in 2002, Teach First’s aim was to encourage more graduates to try teach-ing. Amid worries that the best brains in the country were being lured into the City of London, accountancy and law, the idea was to tap some of their brain power for state schools, in an attempt to tackle educational inequality.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
2. LinkedIn. Brand love: 47% / Rank: 309
Trends and targets in antiviral phototherapy
Will impeachment proceedings begin against Donald Trump
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
That calm can sometimes be taken for a lack of the urgency that is vital in the fast-moving tech industry. Many were disappointed that Apple Watch was not made available to buy this year. But analysts say Apple’s approach of waiting until it has perfected a product usually leads to stronger long-term performance. Samsung, whose smartphone sales have suffered this year, is on its sixth-generation smartwatch, but has still not found a real hit.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
那些原本希望今年凭借战术策略获得些利益的财务顾问和资产配置人员，也在反复无常的市场中栽了跟头。全美前三位的战术策略产品中，有两款产品几乎因为高达两位数的亏损而崩盘，还有一款产品则因为向公众误报自身历史回报率而受到美国证交会调查。另一家战术产品巨头嘉信理财旗下90亿美元的Windhaven Diversified Growth产品，2014年的回报率几乎为零。战术策略原来不过如此。
Diagnostic technologies for COVID-19: a review
Wright is one of the most original figures of British Romantic painting, and this composition, held in the same private collection in Derbyshire since 1840, had an approachable low estimate of 100,000 because of condition issues and — not insignificantly — the fact that it was a charity donation to benefit Syrian refugees. As a result, at least three bidders pushed the price to 665,000 with fees.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
In addition to WeChat's core private and group messaging functions, users can also find new contacts by using the application's Drift Bottle function, where a user records a message and sends it out to see in a virtual bottle for a stranger to pick up and respond. Its Look Around function, similar to some mobile dating applications, allows users to browse the profiles of other users who are in close proximity. It also has a function called Moments that allows users to share photo albums publicly with groups of contacts, much like photo-sharing application Instagram.
BETTER CALL SAUL (AMC, Feb. 8) Vince Gilligan and Peter Gould’s “Breaking Bad” spinoff is probably the most anticipated new series of the winter. Starring Bob Odenkirk as the crooked lawyer Saul Goodman, the show is set before the action of “Breaking Bad,” so any appearances by Bryan Cranston or Aaron Paul would be cameos at best. But the audience favorite Jonathan Banks reprises his role as the phlegmatic enforcer Mike Ehrmantraut.
The president lashed out at the UN on Sunday for voicing human rights concerns over his war on drugs, saying the Philippines might leave the organisation and form a new body with China and African nations.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Apple CEO Tim Cook
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
"He was not on the intelligence services' radar," added the prime minister.
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
“…called the interviewer by the wrong name.”
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
After Google and Apple, are Amazon and Microsoft.
Antiviral drug discovery: broad-spectrum drugs from nature
But Mr Stevenson said “this might reflect that the US is being bolder than the EU in protecting domestic steel producers”.
Against: Strong in many categories, but without quite managing to be a front runner in any. Perhaps Timothee Chalamet's performance is its best chance of awards success.
Influenza neuraminidase: A druggable target for natural products
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
进入前五强的还有桑德拉·布洛克（Sandra Bullock），是我们榜单中仅有的两位女演员之一（另一位是排名第十的詹妮弗·劳伦斯）。布洛克出演了两部电影题材迥异的热门影片：《地心引力》（Gravity）是一部紧张刺激的惊险片，有望使她再次获得奥斯卡提名；而《辣手警花》（The Heat）则是一部票房成绩不俗的喜剧片，全球票房收入达2.3亿美元。
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
A study published in the journal "Clinical Psychological Science" in 2012 showcased the power of self-imagination, which showed the technique could help people with impaired memories, as well as individuals with no memory problems. As with other studies of human memory, the scientists asked participants to remember a list of words related to certain personality traits. The participants were then asked to use a specific strategy to help them recall the words. For example, some participants were asked to remember one personality trait by thinking of a second word that rhymed with the trait. Other participants were asked to remember the definition of the trait while others were asked to engage in "self-referential processing" where they would think about the trait in a personal, self-reflective way.
Frankly, this is unlikely to be ready in time for next year, but we'll include it just in case. The second film from Laszlo Nemes, who won the foreign language Oscar earlier this year for Son of Saul, is a coming-of-age drama set in Budapest just before the first world war.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
The U.S. Congress and the media will go berserk when Goldman announces the size of its 2009 bonus pool. But the outrage will be brief and of little lasting consequence. The 'hate Goldman Sachs' story has been running just too long.
Inhibition of SARS coronavirus helicase by bismuth complexes
Stanford's Zhenan Baohas has developed a super-flexible, super-durable, and super-sensitive material that can be the basis for future synthetic skin. People have tried developing synthetic skin before, but Baohas's material handles touch sensitivity better than any predecessor. It contains organic transistors and a layer of elastic, letting it stretch without taking damage. And it's self-powered—this skin contains a series of elastic solar cells.
阿方索?卡隆(Alfonso Cuaron)凭藉广受好评的全球热门太空科幻影片《地心引力》(Gravity)赢得最佳导演奖。《地心引力》、《美国骗局》和《为奴十二年》均有可能成为今年奥斯卡奖(Academy Awards)的夺奖热门，本周四将公布今年奥斯卡奖提名名单。（与金球奖不同，奥斯卡奖还设置技术类奖项。）
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
The first drone can be traced back to 1916 when British inventor Archibald Low designed and flew the first unmanned radio-controlled vehicle. The drone was made to counterattack German Zeppelin airships, and it also carried out ground attacks during World War I. It was made with wood and tin, its wings taken from the lower wing of another biplane. Overall, the drone was somewhat unsuccessful because the noise from its engine interfered with its radio. The Sopwith Aircraft Company also tried making a drone in 1916. They placed the radio equipment at the tail so that the engine would not interfere with its signal, but their drone never flew as it was damaged in an accident on the ground. Low would try flying his drone again in 1917 when he flew it in front of some senior military officers. It was launched from the back of a lorry and flew for some time before crashing due to engine failure, almost killing the military officers present.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Judge Business School at the University of Cambridge jumps five places to fifth. Not only is it the first time it has broken into the top five, but it is also the first occasion that LBS is not the top-placed UK school in the MBA ranking.
乔布斯在苹果博览会上展示iPod mini ，2004年1月6日，旧金山
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
7. Pemuteran, Indonesia-Bali's pemeturan has sites for scuba diving among coral-covered Buddha statues, while ground-level offerings include beachfront resorts and restaurants.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
In the past two decades, several campus poisoning incidents have sparked mass debates and concerns about students' psychological development and support.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
But retail sales growth softened to 10 per cent in October, betraying economists’ expectations it would hold steady at 10.7 per cent growth from September.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
"Now more attention is being paid to the second generation of stars and rich people, but in fact the second generation of migrant workers needs more attention."
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Over the past three years, drawing conclusions about China's box office growth has been complicated by Beijing's decision to include new service fees in official revenue totals.
In 1995 Dutch troops serving as UN peacekeepers failed to prevent Bosnian Serb forces murdering 8,000 Muslim men and boys in the town of Srebrenica in eastern Bosnia.
联系方式:Staci Donegan and Peter Westley, Celia Dunn Sotheby’s International Realty, (912) 247-2052 / (912) 660-5169; celiadunnsir.com
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
'But then what I do is I nudge him with a little reference to a newspaper article he happens to glance at which just reminds him that these things will give him cancer.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
3. Your boss received your résumé from a contact of a contact。
In the Robot World Cup Soccer final on June 30th the Dutch robots weren’t up against the Chinese team “Water” from Beijing. Within a minute the Chinese team scored a goal. The Dutch made an equalizer before half-time, yet in the second half team Water scored again.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
China does not want to see a trade war between the US and China. That would not make our trade fairer and cause loss for the both sides.
The unemployment rate probably won't fall quite as rapidly in 2015, according to economists, especially if more people enter the labor force because jobs are easier to find. Yet another large spate of hiring similar to the gain in 2014 would make the low unemployment rate more believable.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.
贾斯汀比伯名列第五，因他为慈善组织Pencils of Promise和Believe Charity Drive做的贡献。
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Mila Kunis placed second on the list, followed by Kate Upton, pop star Rihanna and Emma Stone.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Goldie Blox是一家玩具公司，使命是重新定义玩具商店中的“粉红走道”。在科学、技术、工程和数学（STEM）教育和职业领域，男性数量要大大多于女性，大部分女孩往往在八岁前就对这些领域失去了兴趣。Goldie Blox所设计的玩具则通过吸引女孩发展强大的口头及故事讲述能力的方式——同时仍提供机会来发展日后可转化成对工程学兴趣的技能——来鼓励和启发未来的工程师们。说到机会，一家玩具初创企业如何能在和一开始就统治着玩具行业的大公司的抗衡中脱颖而出呢？Goldie Blox走出了明智的一步：最近，该公司发布了一段视频，采用了Beastie Boys的歌曲《女孩们》（Girls）做背景音乐，该视频得到了病毒式传播。尽管这段视频最终被撤下，但Goldie Blox在提高公众对让更多女性和女孩对STEM产生兴趣——以及对Goldie Blox玩具——的认知上，做了一份相当不错的工作。
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
We will boost the development of modern agriculture.
Chinese mainland is home to two of the top three universities in Asia, according to research published last Thursday by the Times Higher Education (THE).
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Its return to the throne came at a cost to London which, after occupying pole position for two years, is trading places with its Asian rival.
A modular microarray imaging system for highly specific COVID-19 antibody testing
She only learnt to walk five months ago, but 'Baby Beyoncé' is already strutting her stuff on stage at pageants.
China’s handling of its state reserves of raw materials such as cotton and sugar will be a key factor shaping the direction of agricultural commodities in 2017, according to a major lender to agribusinesses.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Call Me by Your Name
Will China’s reported gross domestic product growth surpass 6.5 per cent
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Good luck, good health, hood cheer. I wish you a happy New Year.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
That comes in spite of official figures released on Tuesday showing China’s exports had contracted for a second straight month in October, suggesting domestic demand is the main driver of price gains for producers.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
John Stevenage, chief executive of British Mensa, said he was delighted for Nishi. He said: 'I hope she will make full use of her membership to meet new, like-minded people and challenge herself. Joining Mensa opens the door to an international network of more than 100,000 people and many members make friends for life.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
He took out his textbooks and busied himself with his daily homework routine.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
10. “移动珠宝”(Run the Jewels)，《移动珠宝2》，Mass Appeal。说到迫切和讥讽，杀手麦克(Killer Mike)和EL-P都是地下说唱界不同圈子里的资深人士了，他们组成的“移动珠宝”在第二张专辑里找到了坚实的互相吸引。他们的说唱强大有力，关注点狂热喧闹，专辑抨击没有让任何人摆脱困境的权力结构。
Or maybe you've become bolder in arguing against decisions you disagree with, Foss says. "Any variation to what's expected of you or from you could raise an eyebrow," she adds。
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
"I am a doctor and I prefer to speak frankly. A person's health is related first to eating, drinking and air. Any kind of development will be nothing if the quality of food, water and air is not good." ZHONG NANSHAN, NPC deputy and academic with the Chinese Academy of Engineering
LBS’s programmes consistently rank highly for the extent to which alumni reach their targets. “I managed to achieve not only the goals I set for myself but to exceed them with the job I secured,” says one 2010 MBA graduate who responded to the FT survey.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Rossello also has pledged to work closely with a federal control board that U.S. Congress created last year to oversee Puerto Rico’s finances, and he has said he supports negotiations with creditors to help restructure a nearly $70 billion public debt.
《自己土地上的陌生人： 美国右翼的愤怒与哀悼》(Strangers in Their Own Land: Anger and Mourning on the American Right)一书的作者阿莉?罗素?霍克希尔德(Arlie Russell Hochschild)对路易斯安那州的农村社区进行了四年的研究，她认为那里“深藏着”一种失去机会的感觉。
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Writing for a Variety Special: Patton Oswalt, “Patton Oswalt: Talking for Clapping”
Anti-HIV drug repurposing against SARS-CoV-2
However, five Beijing-based travel agents said they were still selling South Korea tours for March, as was China’s largest online travel company Ctrip. Representatives at the top three state-owned airline carriers in China told Bloomberg they had not received instructions to halt ticket sales to the country.
Length-scale dependence of protein hydration-shell density
She is now so successful that her mother has hired a security team who monitor the star 24/7.
Stanford’s alumni have the highest salary on average at $195,000 but overall the top 15 MBA programmes are closely matched in terms of income, career progress and satisfaction. All but one have average alumni salaries greater than $150,000, with a pay increase of about 100 per cent compared with their pre-MBA income.
4. Con Dao Isalsnd, Vietnam-Once the site of the infamous Con Dao prison, Vietnam's isolated archipelago of 16 islands known as the Con Dao Islands is starting to become known for its scenery and fresh seafood.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
《巴克斯托姆》(Backstrom)，Fox，1月22日播出。去年，福克斯推出根据一部澳大利亚电视剧《法庭浪子》(Rake)，由格雷格·金尼尔(Greg Kinnear)主演，讲述一个自毁律师的故事。那部剧没成功，但现在Fox又试着推出了一部根据瑞典系列小说改编的自毁侦探的故事，由《办公室》(The Office)男星雷恩·威尔森(Rainn Wilson)主演。这部剧由Fox的系列剧《识骨寻踪》(Bones)的编剧哈特·汉森(Hart Hanson)主创，但在试播集里，威尔森饰演的巴克斯托姆看上去更像豪斯医生(House)，而不像《识骨寻踪》里的角色。
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
新美国基金会(New America Foundation)高级研究员李?德鲁特曼(Lee Drutman)在一份给Vox的分析文章中指出，在阿肯色州、北卡罗莱纳州和田纳西州，移民人口是1990年的三倍以上。围绕这些变化产生的焦虑或许可以解释共和党为什么在这个阶段更关注限制移民问题，还有这些州的白人投票者们何以压倒性地支持特朗普。
Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.
Kristen Stewart definitely did some 'butt' kicking at the Nickelodeon Kids' Choice Awards 2013 on Saturday. The star strutted down the purple carpet in a dazzlingly deep blue and black top and tiny shorts that had a miniscule checkerboard pattern. Kristen was nominated for two awards at the live show - Favorite Movie Actress for The Twilight Saga: Breaking Dawn - Part 2 and Favorite Female Buttkicker for Snow White and the Huntsman.
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Other notable custom course performances include Harvard Business School, which recorded one of the year’s biggest rises, jumping nine places to fifth. The Massachusetts school was ranked 18th two years ago.
"The Hunger Games" star ranks first on the 2012 edition of AskMen.com's "Top 99 Most Desirable Women" list. The poll, which collected more than 2.4 million votes, asked the website's readers to choose their favorite female celebrities based on their looks, personality, talent and other desirable characteristics.